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Biliopancreatic diversion: sustainable weight loss, but increase in micronutrient deficiencies

Biliopancreatic diversion (BPD) is a complex bariatric operation with good long-term results regarding weight loss. With the increased complexity of this procedure, the risk of secondary effects may also increase. This study addressed clinical results and nutritional complications in 64 morbidly obese patients who were followed up for 3 years after BPD.

Huge health benefits after BPD

BDP proved to be an effective method for losing weight: the excess weight loss increased from 29.3% at 6 months postoperatively to 61.5% at 3 years. Besides the sustainable weight loss, BDP significantly reduced comorbidities as diabetes, hypertension and hyperlipidemia.

Increased prevalence of micronutrient deficiencies

Despite the advised usage of a multivitamin, the prevalence of deficiencies for ferritin, vitamin A, D and B12, zinc and copper increased significantly over the 3-year period. Only folic acid deficiency, which was found in half of the patients before BDP, decreased to 5.5% after 3 years. To reduce the risk of nutritional deficiencies, proper monitoring of the nutritional status is needed. Furthermore, advice for long-term supplementation is essential after BDP to prevent severe clinical and biochemical deficiencies.

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De Luis et al. (2008) Clinical results and nutritional consequences of biliopancreatic diversion: three years of follow-up. Annals of Nutrition and Metabolism, 53: 234-239.

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